1 in 8 women will be diagnosed with invasive breast cancer in her lifetime
Hereditary Breast and Ovarian Cancer
Roughly 15% of women diagnosed with breast cancer have some type of family history of the disease. For a small percentage of these women, there may be a very strong family history of breast cancer and other types or related cancers. This type of cancer develops when there is a change to certain genes that are passed down from a parent to his/her child. Women who have these genetic changes are at higher risk of developing something called Hereditary Breast and Ovarian Cancer (HBOC). It is important to identify these women so they can receive proper management and follow up from their healthcare providers.
Sporadic Breast Cancer
However, up to 85% of breast cancer cases do NOT develop due to an abnormal gene being passed down from a parent to his/her child. Instead, they are caused by a woman’s genetic makeup combined with environmental factors. This type of breast cancer is called sporadic breast cancer and often takes a woman by surprise. As this type of breast cancer often develops without warning, it becomes even more important to identify your risk factors. This will allow your healthcare provider to work with you on creating management plans that can reduce your risk of developing breast cancer.
- BREVAGenplus provides information about breast cancer risk; it does not diagnose breast cancer
- BREVAGenplus is validated in African American, Caucasian, and Hispanic women age 35 years or older
- The risk estimate used in this test does not take into account several other breast cancer risk factors, such as an extensive family history of breast and ovarian cancer
- This test is used for clinical purposes
* BREVAGenplus is not applicable to women who have a personal or extensive family history of breast and/or ovarian cancer, or other high risk factors. In this case, patients would be referred for genetic counseling and risk assessment for hereditary cancers